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derived from a combination of the amino acids phenylalanine and tyrosine, phenethylamine is a common class of psychedelic hallucinogens. it is a very potent form of amphetamine with one of the greatest receptor affinities of any amphetamine derivative. because of its drug potential, the use of phenethylamine is closely regulated in the united states.
e. fischeri a halophilic species that has been a valuable physiological microcosm for studies of metazoan evolution. it is a mutualistic associate of animals, including corals and fish, and has been used as a useful model for studying the effects of low ph on important processes of ecology. this species is also of economic importance in the food industry as the agent used to produce and monitor and the indicator of widely used quality control parameters, particularly the measure of “total viable count” or tvc. phylogenetic analysis shows that e. fischeri is the closest relative of the heterotrophs. genome sequencing of this and other extremophiles reveal diverse and unique pathways of energy conservation and ph homeostasis that may underlie their remarkable properties. further studies using fluorescent markers and immunohistochemical approaches are expected to elucidate the unique environments inhabited by these microbes. as currently understood, e. fischeri is unusual in life-style among bacteria in that it employs proton-driven respiratory membranes to translocate protons across the cytoplasmic membrane, resulting in h+ accumulation and a h+ gradient, and employs a cytoplasmic atp synthase to drive atp synthesis. e. fischeri also uses unique metabolic pathways that incorporate unusual monofunctional pyridines into building blocks, and in this way can synthesize a full complement of peptidoglycans. this bacterium is a key, ubiquitous ecological associate of marine and estuarine organisms, but is not found in fresh water and not associated with any terrestrial organisms.
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